By Charles Dickens

One of 5 loved Christmas classics
First released on December 19, 1843, A Christmas Carol used to be an immediate vintage: Londoners thronged to listen to Dickens learn it in individual and purchased out the 1st printing in days. Its reception was once so ecstatic that it's credited with aiding to restore curiosity one of the Victorians in Christmas traditions, together with caroling and vacation playing cards, in addition to inciting an unforeseen wave of charitable giving from Britain’s business Age robber barons. Originally conceived as a pamphlet opposed to exploitative capitalism ahead of taking its present shape, it has encouraged dozens of theatrical and picture adaptions, and its characters, from Scrooge to Tiny Tim, are endlessly inscribed in our hearts and minds.

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22. Korhonen K, Reijonen TM, Malmstrom K, Klaukka T, Remes K, and Korppi M. Hospitalization trends for paediatric asthma in eastern Finland: a 10-yr survey. Eur Respir J 2002; 19: 1035–1039. 23. Csonka P, Mertsola J, Kaila M, and Ashorn P. Regional variation in the diagnosis of asthma among preschool-age children. Pediatr Allergy Immunol 2000; 11: 189-192. 24. Peat JK, Toelle BG, Marks GB, and Mellis CM. Continuing the debate about measuring asthma in population studies. Thorax 2001; 56: 406–411.

Combined use of exhaled nitric oxide and airway hyperresponsiveness in characterizing asthma in a large population survey. Eur Respir J 2000; 15: 849–855. 11. Sears MR, Jones DT, Holdaway MD, Hewitt CJ, Flannery EM, Herbison GP, and Silva PA. Prevalence of bronchial reactivity to inhaled methacholine in New Zealand children. Thorax 1986; 41: 283–289. 12. Toelle BG, Peat JK, Salome CM, Mellis CM, and Woolcock AJ. Toward a definition of asthma for epidemiology. Am Rev Respir Dis 1992; 146: 633–637.

Very few population-based studies focus on the persistence of childhood asthma. 57,58 Two Australian studies from Tasmania59 and Melbourne60 examined the natural history of asthma in population-based samples. Each study had limitations — the first because it included only a single follow-up some 20 years after the initial survey of 7-year olds, and the second because of the intermixing of an “enriched” cohort of subjects with severe asthma to provide sufficient data for determining outcomes in this end of the spectrum of asthma in the community.

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