By Thul R., Smith G. D., Coombes S.

We current a bidomain fire-diffuse-fire version that enables mathematical research of propagating waves of increased intracellular calcium () in dwelling cells. Modeling unencumber as a threshold procedure permits the categorical building of touring wave strategies to probe the dependence of wave velocity on physiologically very important parameters corresponding to the brink for liberate from the endoplasmic reticulum (ER) to the cytosol, the speed of resequestration from the cytosol to the ER, and the whole [] (cytosolic plus ER). curiously, linear balance research of the bidomain fire-diffuse-fire version predicts the onset of dynamic wave instabilities resulting in the emergence of waves that propagate in a back-and-forth demeanour. Numerical simulations are used to verify the presence of those so-called 'tango waves' and the dependence of wave velocity at the overall [].

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