By W. Schramm, H. Krebs, S. Fleissner (auth.), Professor Dr. med. Inge Scharrer, Professor Dr. med. Wolfgang Schramm (eds.)

This e-book comprises the contributions to the thirtieth Hemophilia Symposium, 1999. the most themes are HIV an infection, inhibitors in hemophilia, glossy therapy of hemophilia, drug-induced thrombophilia and pediatric hemostasiology. the quantity is rounded off via various unfastened papers and posters on hemophilia and linked topics.

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Welte, C. Wermes, Hannover; Rainer Zimmermann, Heidelberg; E. Wenzel, Pindur, Homburg/Saar; EC. Sitzmann, Gerd Dockter, Annegret Seider, Homburg/Saar; E Zind, Karim Kentouche, lena; K. HOffken, K. Wollina, Fricke, Jena; Hirschmann, Frau B. Eggeling, Kassel; UR. D. Bruhn, Kiel; Eckhard Lechler, Koln (Lindenthal); Mario Koksch, Leipzig; Harald Lenk, Leipzig; H. J. Siemens, Lubeck; Peter Hellstern, Ludwigshafen; R. Herbert, Luneburg; D. Franke, Magdeburg; Uwe Mitder, von Aumann, Magdeburg; Volker Kretschmer, Monika Weippert, Marburg; K.

In 26 non-responders the dose was increased to 6 MU thrice weekly for additional 3 months. Only 16% of the patients could be treated successfully, with a sustained response documented 26 weeks after discontinuation of therapy. The high-dose interferon regimen applied in our study with an initial dose of 6 MU daily within the first 4 weeks was not able to induce a higher response rate. Out of the 14 patients, u displayed genotypes la or Ib (79%); 3 patients presented with genotype la (I), genotype 2a (I), and genotype 3a (1).

Heathcote, S. Zeuzem, C. Trepo, and J. Albrecht. 1998. Randomised trial of interferon alpha2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alpha2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (IHIT) [see comments]. Lancet. 352:1426-32. 19. , J. Moussali, V. Ratziu, C. Regimbeau, and P. Opolon. 1999. Effects of interferon therapy in »non responder« patients with chronic hepatitis C. J Hepatol.

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